Novel Chiral Switching Ligands for Enantioselective Asymmetric Reductions of Prochiral Ketones
نویسندگان
چکیده
The newly developed chiral ligands 1 and 4 show opposite enantioselectivity in the asymmetric reduction of prochiral ketones resulting in the production of either enantiomer depending on the metal complex with high enantiomeric excess.
منابع مشابه
Asymmetric synthesis mediated by chiral ligands
Chiral chelated lithium amides were designed and synthesized. Studies have been done to explore the use of these lithium amides or their corresponding amines for enantioselective reactions such as deprotonation of prochiral cyclic ketones, kinetic resolution of racemic 2-substituted cyclohexanones by deprotonation, regioselective deprotonation of optically active 3-keto steroids, alkylation of ...
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